Lion's mane (Hericium erinaceus), belonging to the phylum Basidiomycota, order Fungi, family Hericidae, and genus Hericium, is a medicinal and edible mushroom with a long history of consumption and abundant planting resources in China. Its annual economic value exceeds 500 million US dollars. Lion's mane contains various bioactive ingredients, such as polysaccharides, Hericin erinaceus, Hericin erinaceus ketone, glycoproteins, polyphenols, etc. These bioactive ingredients make lion's mane helpful in preventing, relieving, or treating various diseases including cancer, hyperlipidemia, and neurodegenerative diseases. Due to its nutritional and health benefits, the consumption and research scope of lion's mane has expanded from Asian countries to European and American countries....