Milk thistle is a 1 or 2-year-old herbaceous plant in the Asteraceae family, with a height of 1.0-1.5 meters. It is native to mountainous areas in the Mediterranean, Asia, and North Africa, and is planted around the world. Milk thistle mainly contains flavonoids, terpenes, and fatty acids. Among them, flavonoids are mainly composed of silymarin (70% to 80%), which accounts for 1.5% to 3.0% of the dry weight of the fruit. In addition, milk thistle also contains other flavonoids such as paclitaxel, quercetin, dihydroquercetin, etc. The anti-inflammatory properties and antioxidant activity of silymarin have been well known to the world. For over 2000 years, it has been used to treat liver, kidney, spleen and other diseases, with biological effects such as regulating immunity, clearing free radicals, protecting the liver, anti-tumor, and antioxidant....